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Are You Paying Fat Taxes?
ALSO: GLP-1 Research Roundup, Shortages and a Stanley Giveaway
Welcome to launch day of Beyond the BMI! ๐
๐ค Did you know that skipping sleep can sabotage your weight? Why? Lack of sleep tanks leptin (the "I'm full" hormone) and spikes ghrelin (the "I'm hangry" hormone). Clocking enough shut-eye keeps these hormones in check, making it easier to stick to your health goals. So prioritize that pillow time - your waistline will thank you.
In todayโs email:
GLP Tea & Research Roundup: The latest news and breakthroughs on everything GLP-1.
Eliminating Plateaus: Busting through weight loss plateaus via intermittent fasting.
Caption This: Your GLP-1 shot (pun intended) at winning a free Stanley!
๐ Fat Tax: Gripping stories of larger bodies navigating fat bias in the workplace.
GLP TEA
Today in GLP-1s & Weight Loss
๐ช New Shot Spares Muscle: Researchers are cooking up an injectable called pemvidutide that melts fat while keeping muscle. In trials, patients dropped up to 16.5% of their weight - like getting the perks of 150 mins of exercise a week without hitting the gym.
๐ Mounjaro Supply Crunch: Brace yourself for a Mounjaro shortage throughout April. Unprecedented demand is outstripping production, says the FDA.
โค๏ธ Wegovy's Heart Perks: Wegovy scored FDA approval to treat heart disease in seniors on Medicare. In trials, it slashed heart attack and stroke risk by 20%.
๐ Amazon's GLP-1 Play: Eli Lilly is teaming up with Amazon Pharmacy to streamline access to their GLP-1 meds like Mounjaro and Zepbound.
๐ Costco's Ozempic Deal: Ozempic is hitting Costco shelves thanks to a collab with Sesame. But hold the applause - the $179 savings over 3 months might not offset the hefty $950-$1,600 monthly price tag for the uninsured.
๐น Brozempic Aims at Men: Startup Fella Health is riding the GLP-1 wave with Ozempic and other weight loss drugs marketed squarely at men. Will "Brozempic" get guys on board? TBD.
RESEARCH ROUNDUP
Cutting-Edge Findings on GLP-1s Beyond Weight Loss
๐ง GLP-1s: MS Game-Changer?
A deep dive into FDA data found obesity meds that rev up GLP-1 receptors (think dulaglutide, liraglutide) slashed the risk of developing MS by a whopping 39% vs. control drugs. Promising stuff.
๐ฅ Lixisenatide vs. Parkinson's
In a phase 2 trial of 156 patients, the GLP-1 diabetes med lixisenatide kept motor symptoms from getting worse over a year. The placebo group? Not so lucky - they saw a clinically meaningful 3-point decline on a Parkinson's motor scale.
But don't break out the champagne just yet. Larger, longer phase 3 studies (like the ongoing exenatide trial) are still needed to seal the deal. Stay tuned.
FROM THE BLOG
Escaping Weight Loss Plateaus with Intermittent Fasting
If you've hit a frustrating weight loss wall on your GLP-1 weight loss journey, you're not alone. It's a common roadblock, but there's a powerful tool that can help you bust through those plateaus: intermittent fasting.
I've put together a comprehensive guide on how strategic meal timing works hand-in-hand with any GLP-1 to reignite fat loss and keep those results coming. Here are a few key takeaways:
Intermittent fasting helps regulate insulin levels, which is crucial for fat burning and weight loss.
By sticking to designated eating windows and avoiding snacks in between, you give your body the green light to torch fat for fuel.
Ease into fasting gradually, stay hydrated during fasting periods, and focus on nutrient-dense foods during eating windows for best results.
Be patient and consistent - it may take a few weeks for your body to adapt, but the payoff is worth it.
Always listen to your body and consult with your healthcare team before making significant changes to your eating habits.
If you're ready to dive deeper into how intermittent fasting can supercharge your weight loss results on GLP-1s, check out the full blog post here. I cover the science behind why it works, a sample meal timing schedule to get started, and tips for success.
Keep pushing forward - your breakthrough is coming.
CAPTION THIS
Unleash Your Inner Comedian for a Chance to Win!
To celebrate the launch of the Beyond the BMI newsletter, weโre holding a caption contest. Hereโs how it will work:
Take a look at the picture below of your friendly neighborhood pharmacist overwhelmed by the surge in GLP-1 demand.
Come up with your wittiest, most side-splitting caption and reply to this newsletter via email with your entry by 6 pm ET Saturday, 4/13.
I'll comb through the submissions and pick the top 5 that really tickle my funny bone.
Those chosen few will be entered into a random digital drawing, and one lucky winner will be crowned the Caption King or Queen, complete with bragging rights, announced in next weekโs newsletter.
But wait, there's more! The winner will also score a free 24 oz Stanley The Quick Flip Go Bottle in their color of choice (a $25 value). Not too shabby for flexing your comedic chops.
Alright, time to get those creative juices flowing and give me your best shot. I can't wait to see what you come up with!
The GLP-1 Pharmacistโs POV
GLP-1 Around the Web
World Wide GLP-1 Success Stories
@hopiedopiee1 #wegovy #glp1forweightloss #weightloss #weightlossprogress #weightlosstransformation #wegovyshot #insulinresistance #metformin #glp1
Everyone keeps talking about lean mass loss with GLP-1 agonists, meanwhile I have patients on GLP-1s doing deadlift competitions and getting stronger.
โ Dr. Spencer Nadolsky (@DrNadolsky)
2:49 PM โข Apr 2, 2024
Progress Prompt of the Week
Celebrating our Non-Scale Victories
Coming Soon
Whatโs on the Horizon at Beyond the BMI
Whatโs Next?
๐ Side effects and insurance getting you down? Fresh blog posts detailing how to smooth out those rough patches are coming soon.
๐๏ธ Craving more of The Obesity Onion? A podcast hub is nearly ready for you to binge away and even leave your own two cents.
๐ค Spread the word and enhance your GLP-1 setup. Details on our new referral program with seriously valuable GLP-1 merch rewards drop next week.
๐ Thatโs all for now
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Thanks for reading.
Until next time!
P.S. For questions and feedback, email me directly at [email protected]. I always listen and respond.
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